‘Landmark study’ shows brain cells revamp their DNA, perhaps sparking Alzheimer’s disease

‘Landmark study’ shows brain cells revamp their DNA, perhaps sparking Alzheimer’s disease https://cdn.disclose.tv/sites/default/files/styles/og_image/public/img/post/2018/11/21/ss2116497-1280x720.jpg?itok=dc4TV5FR

‘Landmark study’ shows brain cells revamp their DNA, perhaps sparking Alzheimer’s disease


The scientists’ new analysis, reported online today in Nature, shows the neurons seem to carry not one or two variants of the APP gene, but thousands. Some changes involved switching single nucleotide bases, the DNA subunits that make up the genetic code. In some cases, the APP gene variants had jettisoned chunks of DNA, and the remaining sections had knitted together.

www.sciencemag.org/...



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