A cellular mechanism of the bacterium Escherichia coli can serve to stop multiresistant bacteria

A cellular mechanism of the bacterium Escherichia coli can serve to stop multiresistant bacteria https://noticiasdelaciencia.com/upload/images/12_2018/1618_un-mecanismo-celular-de-la-bacteria.jpg?43

A cellular mechanism of the bacterium Escherichia coli can serve to stop multiresistant bacteria





Researchers at the University of Newcastle in collaboration with Miguel Vicente's group at the National Center for Biotechnology (CSIC) in Spain have found proteins that participate in a new molecular mechanism that regulates the start of cell division of E. coli. The proteins involved in this process could serve as a target in future strategies for the production of new antibiotics to stop multiresistant bacteria. The results are published in the journal Nature Communications.


"Cell division is a critical process for bacterial survival. In addition to controlling the distribution of genetic content, the cell itself must be divided, for which the cell membrane has to be strangulated without losing intracellular pressure ", explains Miguel Vicente, from the National Center for Biotechnology, who has participated in this study carried out in collaboration with researchers from the University of Newcastle (United Kingdom).

 



Image of bacteria Escherichia coli in the process of active growth. (Photo: CNB)

 

"The bacterium resists this pressure thanks to a supramolecule that covers the membrane like a corset," explains the researcher. This wrap lengthens during bacterial growth as the length of the bacterium increases and everything helps to maintain a balance. During cell division, this equilibrium must be readjusted to separate the daughter cells, and mechanisms are triggered that change the arrangement of the supramolecule, simultaneously with the strangulation of the membrane. During the whole process the membrane is stable and no breakage occurs that would kill the bacteria.


In this work, researchers have found that in E. coli, the molecular processes necessary for the beginning of this process to be effective are duplicated. "There is thus no single machinery to regulate the efficiency of cell division, but there are pieces that can replace one another, so that if one fails, there is an extra security system to guarantee the final success of the process," concludes Miguel Vicente. (Source: CSIC / DICYT)
    .


SOURCE LINK THE BEST ONLINE UFO WEBSITES 
https://www.beviral.online